Moccasin is located in Judith Basin County and began as a homestead community. In 1908 the Montana State legislature created the Central Montana Agriculture Research Center, 3 miles east of Moccasin. The purpose of the center was to teach dry land farming techniques to the newly arrived homesteaders. Even after the homesteaders bust, the center went on to develop machinery and new crops, improving the area's wheat yields.
Moccasin is located in central area of Montana, west of Lewistown on Highway 87.